The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

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Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells.

In Drosophila, the chromosomal region 75C1-2 contains at least three genes, reaper (rpr), head involution defective (hid), and grim, that have important functions in the activation of programmed cell death. To better understand how cells are killed by these genes, we have utilized a well defined set of embryonic central nervous system midline cells that normally exhibit a specific pattern of gl...

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ژورنال

عنوان ژورنال: Genes & Development

سال: 1995

ISSN: 0890-9369

DOI: 10.1101/gad.9.14.1694